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CRISPR/Cas9-Mediated Biallelic Knockout of IRX3 Reduces the Production and Survival of Somatic Cell-Cloned Bama Minipigs

SIMPLE SUMMARY: Bama minipigs are a local pig breed that is unique to China and possess several negative features, including high fat content, low feed utilization rate, and slow growth rate. The iroquois homeobox 3 (IRX3) gene has been implicated in human obesity and controls body mass and composit...

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Detalles Bibliográficos
Autores principales: Zhu, Xiangxing, Wei, Yanyan, Zhan, Qunmei, Yan, Aifen, Feng, Juan, Liu, Lian, Tang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142520/
https://www.ncbi.nlm.nih.gov/pubmed/32192102
http://dx.doi.org/10.3390/ani10030501