27-Hydroxycholesterol-induced EndMT acts via STAT3 signaling to promote breast cancer cell migration by altering the tumor microenvironment

Objective: The endothelial to mesenchymal transition (EndMT) plays a major role in cancer metastasis by regulating the complexity of the tumor microenvironment (TME). Here, we investigated whether 27-hydroxycholesterol (27HC) induces EndMT in endothelial cells (ECs). Methods: EndMT markers in the hu...

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Detalles Bibliográficos
Autores principales: Jiao, Kailin, Zhen, Jing, Wu, Maoxuan, Teng, Mengying, Yang, Keke, Zhou, Qian, Hu, Chunyan, Zhou, Ming, Li, Yuan, Li, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142833/
https://www.ncbi.nlm.nih.gov/pubmed/32296578
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142833/
https://www.ncbi.nlm.nih.gov/pubmed/32296578
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0262

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