Site-Specific Interactions with Copper Promote Amyloid Fibril Formation for λ6aJL2-R24G

[Image: see text] Light-chain amyloidosis (AL) is one of the most common systemic amyloidoses, and it is characterized by the deposition of immunoglobulin light chain (LC) variable domains as insoluble amyloid fibers in vital organs and tissues. The recombinant protein 6aJL2-R24G contains λ6a and JL...

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Detalles Bibliográficos
Autores principales: Pelaez-Aguilar, Angel E., Valdés-García, Gilberto, French-Pacheco, Leidys, Pastor, Nina, Amero, Carlos, Rivillas-Acevedo, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143407/
https://www.ncbi.nlm.nih.gov/pubmed/32280849
http://dx.doi.org/10.1021/acsomega.9b03220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143407/
https://www.ncbi.nlm.nih.gov/pubmed/32280849
http://dx.doi.org/10.1021/acsomega.9b03220

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