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Site-Specific Interactions with Copper Promote Amyloid Fibril Formation for λ6aJL2-R24G
[Image: see text] Light-chain amyloidosis (AL) is one of the most common systemic amyloidoses, and it is characterized by the deposition of immunoglobulin light chain (LC) variable domains as insoluble amyloid fibers in vital organs and tissues. The recombinant protein 6aJL2-R24G contains λ6a and JL...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143407/ https://www.ncbi.nlm.nih.gov/pubmed/32280849 http://dx.doi.org/10.1021/acsomega.9b03220 |