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Synthesis and Biological Evaluation of Antibody Drug Conjugates Based on an Antibody Expression System: Conamax

[Image: see text] Antibody production for ADCs (or in general) is commonly performed by CHO-based platforms and limited by volumetric productivity, expensive downstream purification, and extended optimization timelines. The Conamax platform is a novel microbial-based protein production and secretion...

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Detalles Bibliográficos
Autores principales: Tawfiq, Zhala, Caiazza, Nicky C., Kambourakis, Spiros, Matsuda, Yutaka, Griffin, Benjamin, Lippmeier, J. Casey, Mendelsohn, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143411/
https://www.ncbi.nlm.nih.gov/pubmed/32280859
http://dx.doi.org/10.1021/acsomega.9b03628