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Identification and in vitro Characterization of a Novel Phage Endolysin that Targets Gram-Negative Bacteria

Most double-stranded (ds) DNA phages utilize holin proteins to secrete endolysin for host peptidoglycan lysis. In contrast, several holin-independent endolysins with secretion sequences or signal-arrest-release (SAR) sequences are secreted via the Sec pathway. In this study, we characterized a novel...

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Detalles Bibliográficos
Autores principales: Bai, Jaewoo, Lee, Sangmi, Ryu, Sangryeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143992/
https://www.ncbi.nlm.nih.gov/pubmed/32245284
http://dx.doi.org/10.3390/microorganisms8030447