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Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs

Roughly a third of the world’s population is estimated to have latent Mycobacterium tuberculosis infection, being at risk of developing active tuberculosis (TB) during their lifetime. Given the inefficacy of prophylactic measures and the increase of drug-resistant M. tuberculosis strains, there is a...

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Detalles Bibliográficos
Autores principales: Nunes, José E. S., Duque, Mario A., de Freitas, Talita F., Galina, Luiza, Timmers, Luis F. S. M., Bizarro, Cristiano V., Machado, Pablo, Basso, Luiz A., Ducati, Rodrigo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144000/
https://www.ncbi.nlm.nih.gov/pubmed/32168746
http://dx.doi.org/10.3390/molecules25061259