Cargando…

Long non-coding RNA PVT1, a molecular sponge of miR-26b, is involved in the progression of hyperglycemia-induced collagen degradation in human chondrocytes by targeting CTGF/TGF-β signal ways

The current study was conducted to investigate the role of long non-coding RNA PVT1 in hyperglycemia-triggered human osteoarthritis (OA) chondrocytes. Cartilage from knee OA patients with and without diabetes, as well as normal cartilage, was obtained. Isolated human chondrocytes were treated with 3...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Luo-Bin, Li, Yao, Liu, Guang-Yuan, Li, Tai-Hang, Li, Feng, Guan, Jian, Wang, Hua-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144035/
https://www.ncbi.nlm.nih.gov/pubmed/31625803
http://dx.doi.org/10.1177/1753425919881778