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Long non-coding RNA PVT1, a molecular sponge of miR-26b, is involved in the progression of hyperglycemia-induced collagen degradation in human chondrocytes by targeting CTGF/TGF-β signal ways

The current study was conducted to investigate the role of long non-coding RNA PVT1 in hyperglycemia-triggered human osteoarthritis (OA) chondrocytes. Cartilage from knee OA patients with and without diabetes, as well as normal cartilage, was obtained. Isolated human chondrocytes were treated with 3...

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Detalles Bibliográficos
Autores principales: Ding, Luo-Bin, Li, Yao, Liu, Guang-Yuan, Li, Tai-Hang, Li, Feng, Guan, Jian, Wang, Hua-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144035/
https://www.ncbi.nlm.nih.gov/pubmed/31625803
http://dx.doi.org/10.1177/1753425919881778

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