Nasal delivery of a CRMP2-derived CBD3 adenovirus improves cognitive function and pathology in APP/PS1 transgenic mice

Calcium dysregulation is a key pathological event in Alzheimer’s disease (AD). In studying approaches to mitigate this calcium overload, we identified the collapsin response mediator protein 2 (CRMP2), an axonal guidance protein that participates in synapse dynamics by interacting with and regulatin...

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Detalles Bibliográficos
Autores principales: Qi, Baochang, Yang, Yu, Cheng, Yingying, Sun, Di, Wang, Xu, Khanna, Rajesh, Ju, Weina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144060/
https://www.ncbi.nlm.nih.gov/pubmed/32272942
http://dx.doi.org/10.1186/s13041-020-00596-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144060/
https://www.ncbi.nlm.nih.gov/pubmed/32272942
http://dx.doi.org/10.1186/s13041-020-00596-3

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