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Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects

Release of insect pests carrying the dominant lethal tetracycline transactivator (tTA) overexpression system has been proposed as a means for population suppression. High levels of the tTA transcription factor are thought to be toxic due to either transcriptional squelching or interference with prot...

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Detalles Bibliográficos
Autores principales: Knudsen, Katherine E., Reid, William R., Barbour, Traci M., Bowes, Laci M., Duncan, Juliana, Philpott, Elaina, Potter, Samantha, Scott, Maxwell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144068/
https://www.ncbi.nlm.nih.gov/pubmed/32019873
http://dx.doi.org/10.1534/g3.120.400990