Cargando…

A Halogen Bonding Perspective on Iodothyronine Deiodinase Activity

Iodothyronine deiodinases (Dios) are involved in the regioselective removal of iodine from thyroid hormones (THs). Deiodination is essential to maintain TH homeostasis, and disruption can have detrimental effects. Halogen bonding (XB) to the selenium of the selenocysteine (Sec) residue in the Dio ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Marsan, Eric S., Bayse, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144113/
https://www.ncbi.nlm.nih.gov/pubmed/32183289
http://dx.doi.org/10.3390/molecules25061328