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Synthesis, Characterization, and Biological Evaluation of Novel 7-Oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic Acid Derivatives

A series of novel 7-oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic acid derivatives was synthesized in good yields by a multi-step procedure that included the generation of the S-alkylated derivatives from 6-substituted arylmethyl-3-mercapto-1,2,4-triazin-5-ones with ethyl 2-chloroacetoacetate,...

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Detalles Bibliográficos
Autores principales: Cai, Dong, Li, Tai, Xie, Qian, Yu, Xiaofei, Xu, Wei, Chen, Yu, Jin, Zhe, Hu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144117/
https://www.ncbi.nlm.nih.gov/pubmed/32182992
http://dx.doi.org/10.3390/molecules25061307