The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys

Naloxone (NLX) is a mu receptor antagonist used to treat acute opioid overdoses. Currently approved doses of naloxone to treat opioid overdoses are 4 mg intranasal (IN) and 2 mg intramuscular (IM). However, higher mu receptor occupancy (RO) may be required to treat overdoses due to more potent synth...

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Detalles Bibliográficos
Autores principales: Scott, Peter J. H., Koeppe, Robert A., Shao, Xia, Rodnick, Melissa E., Sowa, Alexandra R., Henderson, Bradford D., Stauff, Jenelle, Sherman, Phillip S., Arteaga, Janna, Carlo, Dennis J., Moss, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144122/
https://www.ncbi.nlm.nih.gov/pubmed/32192089
http://dx.doi.org/10.3390/molecules25061360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144122/
https://www.ncbi.nlm.nih.gov/pubmed/32192089
http://dx.doi.org/10.3390/molecules25061360

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