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The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys
Naloxone (NLX) is a mu receptor antagonist used to treat acute opioid overdoses. Currently approved doses of naloxone to treat opioid overdoses are 4 mg intranasal (IN) and 2 mg intramuscular (IM). However, higher mu receptor occupancy (RO) may be required to treat overdoses due to more potent synth...
Autores principales: | Scott, Peter J. H., Koeppe, Robert A., Shao, Xia, Rodnick, Melissa E., Sowa, Alexandra R., Henderson, Bradford D., Stauff, Jenelle, Sherman, Phillip S., Arteaga, Janna, Carlo, Dennis J., Moss, Ronald B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144122/ https://www.ncbi.nlm.nih.gov/pubmed/32192089 http://dx.doi.org/10.3390/molecules25061360 |
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