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The Accumulation of Psoralen Contributes to Its Hepatotoxicity Revealed by Pharmacokinetic and Toxicokinetic Study after Repeated Administration

[Image: see text] Psoralen is a furanocoumarin compound found in many herb medicines and is claimed to contribute to the hepatotoxicity caused by lots of traditional Chinese medicine. So far, there has been no research on the differences in pharmacokinetics of single and repeated dosing of psoralen....

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Detalles Bibliográficos
Autores principales: Yang, Li, Yu, Ying-li, Cheng, Li-yuan, Zhang, Pan-yang, Zhang, Yue, Zhou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144168/
https://www.ncbi.nlm.nih.gov/pubmed/32280872
http://dx.doi.org/10.1021/acsomega.9b04153