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The Accumulation of Psoralen Contributes to Its Hepatotoxicity Revealed by Pharmacokinetic and Toxicokinetic Study after Repeated Administration
[Image: see text] Psoralen is a furanocoumarin compound found in many herb medicines and is claimed to contribute to the hepatotoxicity caused by lots of traditional Chinese medicine. So far, there has been no research on the differences in pharmacokinetics of single and repeated dosing of psoralen....
Autores principales: | Yang, Li, Yu, Ying-li, Cheng, Li-yuan, Zhang, Pan-yang, Zhang, Yue, Zhou, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144168/ https://www.ncbi.nlm.nih.gov/pubmed/32280872 http://dx.doi.org/10.1021/acsomega.9b04153 |
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