Design, synthesis and antifungal activity of threoninamide carbamate derivatives via pharmacophore model

Thirty-six novel threoninamide carbamate derivatives were designed and synthesised using active fragment-based pharmacophore model. Antifungal activities of these compounds were tested against Oomycete fungi Phytophthora capsici in vitro and in vivo. Interestingly, compound I-1, I-2, I-3, I-6 and I-...

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Detalles Bibliográficos
Autores principales: Du, Xiu-Jiang, Peng, Xing-Jie, Zhao, Rui-Qi, Zhao, Wei-Guang, Dong, Wei-Li, Liu, Xing-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144198/
https://www.ncbi.nlm.nih.gov/pubmed/32148108
http://dx.doi.org/10.1080/14756366.2020.1729144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144198/
https://www.ncbi.nlm.nih.gov/pubmed/32148108
http://dx.doi.org/10.1080/14756366.2020.1729144

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