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Design, synthesis and antifungal activity of threoninamide carbamate derivatives via pharmacophore model
Thirty-six novel threoninamide carbamate derivatives were designed and synthesised using active fragment-based pharmacophore model. Antifungal activities of these compounds were tested against Oomycete fungi Phytophthora capsici in vitro and in vivo. Interestingly, compound I-1, I-2, I-3, I-6 and I-...
Autores principales: | Du, Xiu-Jiang, Peng, Xing-Jie, Zhao, Rui-Qi, Zhao, Wei-Guang, Dong, Wei-Li, Liu, Xing-Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144198/ https://www.ncbi.nlm.nih.gov/pubmed/32148108 http://dx.doi.org/10.1080/14756366.2020.1729144 |
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