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Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells

Infection of influenza A virus (IAV) can trigger exaggerated pulmonary inflammation and induce acute lung injury (ALI). Limiting IAV replication and alleviation of pulmonary inflammation are two important therapeutic strategies for influenza virus infection. Recent studies have shown that hypoxia in...

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Detalles Bibliográficos
Autores principales: Zhao, Caiqi, Chen, Jie, Cheng, Lianping, Xu, Kaifeng, Yang, Yiyu, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144238/
https://www.ncbi.nlm.nih.gov/pubmed/32208814
http://dx.doi.org/10.1080/22221751.2020.1742585