Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen

Inhibition of fatty acid amide hydrolase (FAAH) reduces the gastrointestinal damage produced by non-steroidal anti-inflammatory agents such as sulindac and indomethacin in experimental animals, suggesting that a dual-action FAAH-cyclooxygenase (COX) inhibitor could have useful therapeutic properties...

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Detalles Bibliográficos
Autores principales: Deplano, Alessandro, Karlsson, Jessica, Svensson, Mona, Moraca, Federica, Catalanotti, Bruno, Fowler, Christopher J., Onnis, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144264/
https://www.ncbi.nlm.nih.gov/pubmed/32200655
http://dx.doi.org/10.1080/14756366.2020.1743283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144264/
https://www.ncbi.nlm.nih.gov/pubmed/32200655
http://dx.doi.org/10.1080/14756366.2020.1743283

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