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Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen
Inhibition of fatty acid amide hydrolase (FAAH) reduces the gastrointestinal damage produced by non-steroidal anti-inflammatory agents such as sulindac and indomethacin in experimental animals, suggesting that a dual-action FAAH-cyclooxygenase (COX) inhibitor could have useful therapeutic properties...
Autores principales: | Deplano, Alessandro, Karlsson, Jessica, Svensson, Mona, Moraca, Federica, Catalanotti, Bruno, Fowler, Christopher J., Onnis, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144264/ https://www.ncbi.nlm.nih.gov/pubmed/32200655 http://dx.doi.org/10.1080/14756366.2020.1743283 |
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