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Effects of naringenin on the pharmacokinetics of tofacitinib in rats

CONTEXT: Naringenin and tofacitinib are often used together for treatment of rheumatoid arthritis in Chinese clinics. OBJECTIVE: This experiment investigates the effect of naringenin on the pharmacokinetics of tofacitinib in rats. MATERIALS AND METHODS: Twelve Sprague-Dawley rats were randomly divid...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Shen, Jiquan, Zhou, Quan, Meng, Deru, He, Youwu, Chen, Feifei, Wang, Shuanghu, Ji, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144329/
https://www.ncbi.nlm.nih.gov/pubmed/32202190
http://dx.doi.org/10.1080/13880209.2020.1738504