Cargando…

Identification of Interleukin-8-Reducing Lead Compounds Based on SAR Studies on Dihydrochalcone-Related Compounds in Human Gingival Fibroblasts (HGF-1 cells) In Vitro

Background: In order to identify potential activities against periodontal diseases, eighteen dihydrochalcones and structurally related compounds were tested in an established biological in vitro cell model of periodontal inflammation using human gingival fibroblasts (HGF-1 cells). Methods: Subsequen...

Descripción completa

Detalles Bibliográficos
Autores principales: Schueller, Katharina, Hans, Joachim, Pfeiffer, Stefanie, Walker, Jessica, Ley, Jakob P., Somoza, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144391/
https://www.ncbi.nlm.nih.gov/pubmed/32197426
http://dx.doi.org/10.3390/molecules25061382