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Identification of Interleukin-8-Reducing Lead Compounds Based on SAR Studies on Dihydrochalcone-Related Compounds in Human Gingival Fibroblasts (HGF-1 cells) In Vitro
Background: In order to identify potential activities against periodontal diseases, eighteen dihydrochalcones and structurally related compounds were tested in an established biological in vitro cell model of periodontal inflammation using human gingival fibroblasts (HGF-1 cells). Methods: Subsequen...
Autores principales: | Schueller, Katharina, Hans, Joachim, Pfeiffer, Stefanie, Walker, Jessica, Ley, Jakob P., Somoza, Veronika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144391/ https://www.ncbi.nlm.nih.gov/pubmed/32197426 http://dx.doi.org/10.3390/molecules25061382 |
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