A Novel Alternative in the Treatment of Detrusor Overactivity? In Vivo Activity of O-1602, the Newly Synthesized Agonist of GPR55 and GPR18 Cannabinoid Receptors

The aim of the research was to assess the impact of O-1602—novel GPR55 and GPR18 agonist—in the rat model of detrusor overactivity (DO). Additionally, its effect on the level of specific biomarkers was examined. To stimulate DO, 0.75% retinyl acetate (RA) was administered to female rats’ bladders. O...

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Detalles Bibliográficos
Autores principales: Wróbel, Andrzej, Szopa, Aleksandra, Serefko, Anna, Poleszak, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144400/
https://www.ncbi.nlm.nih.gov/pubmed/32197469
http://dx.doi.org/10.3390/molecules25061384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144400/
https://www.ncbi.nlm.nih.gov/pubmed/32197469
http://dx.doi.org/10.3390/molecules25061384

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