Cargando…

Synthesis, Characterization and Biological Evaluation of Novel Dihydropyranoindoles Improving the Anticancer Effects of HDAC Inhibitors

The dihydropyranoindole scaffold was identified as a promising target for improving the anti-cancer activity of HDAC inhibitors from the preliminary screening of a library of compounds. A suitable methodology has been developed for the preparation of novel dihydropyranoindoles via the Hemetsberger i...

Descripción completa

Detalles Bibliográficos
Autores principales: Bingul, Murat, Arndt, Greg M., Marshall, Glenn M., Cheung, Belamy B., Kumar, Naresh, Black, David StC.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144403/
https://www.ncbi.nlm.nih.gov/pubmed/32197360
http://dx.doi.org/10.3390/molecules25061377