Tumor-derived soluble CD155 inhibits DNAM-1–mediated antitumor activity of natural killer cells

CD155 is a ligand for DNAM-1, TIGIT, and CD96 and is involved in tumor immune responses. Unlike mouse cells, human cells express both membranous CD155 and soluble CD155 (sCD155) encoded by splicing isoforms of CD155. However, the role of sCD155 in tumor immunity remains unclear. Here, we show that,...

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Detalles Bibliográficos
Autores principales: Okumura, Genki, Iguchi-Manaka, Akiko, Murata, Rikito, Yamashita-Kanemaru, Yumi, Shibuya, Akira, Shibuya, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144518/
https://www.ncbi.nlm.nih.gov/pubmed/32040157
http://dx.doi.org/10.1084/jem.20191290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144518/
https://www.ncbi.nlm.nih.gov/pubmed/32040157
http://dx.doi.org/10.1084/jem.20191290

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