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The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens

Macrophages play pleiotropic roles in maintaining the balance between immune tolerance and inflammatory responses in the gut. Here, we identified transcription factor RBP-J as a crucial regulator of colonic macrophage–mediated immune responses against the enteric pathogen Citrobacter rodentium. In t...

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Detalles Bibliográficos
Autores principales: Kang, Lan, Zhang, Xiang, Ji, Liangliang, Kou, Tiantian, Smith, Sinead M., Zhao, Baohong, Guo, Xiaohuan, Pineda-Torra, Inés, Wu, Li, Hu, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144519/
https://www.ncbi.nlm.nih.gov/pubmed/31944217
http://dx.doi.org/10.1084/jem.20190762