Cargando…

Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model

Alzheimer’s disease (AD) is accompanied by a robust inflammatory response mediated by plaque-associated myeloid cells of the brain. These cells exhibit altered gene expression profiles and serve as a barrier, preventing neuritic dystrophy. The origin of these cells has been controversial and is of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Reed-Geaghan, Erin G., Croxford, Andrew L., Becher, Burkhard, Landreth, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144522/
https://www.ncbi.nlm.nih.gov/pubmed/31967645
http://dx.doi.org/10.1084/jem.20191374