Cargando…

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

Every day, megakaryocytes produce billions of platelets that circulate for several days and eventually are cleared by the liver. The exact removal mechanism, however, remains unclear. Loss of sialic acid residues is thought to feature in the aging and clearance of platelets. Using state-of-the-art s...

Descripción completa

Detalles Bibliográficos
Autores principales: Deppermann, Carsten, Kratofil, Rachel M., Peiseler, Moritz, David, Bruna A., Zindel, Joel, Castanheira, Fernanda Vargas E Silva, van der Wal, Fardau, Carestia, Agostina, Jenne, Craig N., Marth, Jamey D., Kubes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144524/
https://www.ncbi.nlm.nih.gov/pubmed/31978220
http://dx.doi.org/10.1084/jem.20190723