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Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets
Every day, megakaryocytes produce billions of platelets that circulate for several days and eventually are cleared by the liver. The exact removal mechanism, however, remains unclear. Loss of sialic acid residues is thought to feature in the aging and clearance of platelets. Using state-of-the-art s...
Autores principales: | Deppermann, Carsten, Kratofil, Rachel M., Peiseler, Moritz, David, Bruna A., Zindel, Joel, Castanheira, Fernanda Vargas E Silva, van der Wal, Fardau, Carestia, Agostina, Jenne, Craig N., Marth, Jamey D., Kubes, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144524/ https://www.ncbi.nlm.nih.gov/pubmed/31978220 http://dx.doi.org/10.1084/jem.20190723 |
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