2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication

The persistence of the AIDS epidemic, and the life-long treatment required, indicate the constant need of novel HIV-1 inhibitors. In this scenario the HIV-1 Reverse Transcriptase (RT)-associated ribonuclease H (RNase H) function is a promising drug target. Here we report a series of compounds, devel...

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Detalles Bibliográficos
Autores principales: Corona, Angela, Onnis, Valentina, Del Vecchio, Claudia, Esposito, Francesca, Cheng, Yung-Chi, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144554/
https://www.ncbi.nlm.nih.gov/pubmed/32183488
http://dx.doi.org/10.3390/molecules25061338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144554/
https://www.ncbi.nlm.nih.gov/pubmed/32183488
http://dx.doi.org/10.3390/molecules25061338

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