ELMO2 association with Gαi2 regulates pancreatic cancer cell chemotaxis and metastasis

BACKGROUND: Pancreatic cancer is a highly lethal disease. Nearly half of the patients have distant metastasis and remain asymptomatic. Emerging evidence suggests that the chemokine, CXCL12, has a role in cancer metastasis. The interaction between CXCL12 and CXCR4 activates heterotrimeric G proteins,...

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Detalles Bibliográficos
Autores principales: Wang, Yecheng, Li, Hongyan, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144586/
https://www.ncbi.nlm.nih.gov/pubmed/32292657
http://dx.doi.org/10.7717/peerj.8910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144586/
https://www.ncbi.nlm.nih.gov/pubmed/32292657
http://dx.doi.org/10.7717/peerj.8910

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