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ELMO2 association with Gαi2 regulates pancreatic cancer cell chemotaxis and metastasis
BACKGROUND: Pancreatic cancer is a highly lethal disease. Nearly half of the patients have distant metastasis and remain asymptomatic. Emerging evidence suggests that the chemokine, CXCL12, has a role in cancer metastasis. The interaction between CXCL12 and CXCR4 activates heterotrimeric G proteins,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144586/ https://www.ncbi.nlm.nih.gov/pubmed/32292657 http://dx.doi.org/10.7717/peerj.8910 |