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Applying next-generation sequencing to unravel the mutational landscape in viral quasispecies

Next-generation sequencing (NGS) has revolutionized the scale and depth of biomedical sciences. Because of its unique ability for the detection of sub-clonal variants within genetically diverse populations, NGS has been successfully applied to analyze and quantify the exceptionally-high diversity wi...

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Detalles Bibliográficos
Autores principales: Lu, I-Na, Muller, Claude P., He, Feng Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144618/
https://www.ncbi.nlm.nih.gov/pubmed/32278821
http://dx.doi.org/10.1016/j.virusres.2020.197963