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A possible strategy to fight COVID-19: Interfering with spike glycoprotein trimerization

The recent release of COVID-19 spike glycoprotein allows detailed analysis of the structural features that are required for stabilizing the infective form of its quaternary assembly. Trying to disassemble the trimeric structure of COVID-19 spike glycoprotein, we analyzed single protomer surfaces sea...

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Detalles Bibliográficos
Autores principales: Bongini, Pietro, Trezza, Alfonso, Bianchini, Monica, Spiga, Ottavia, Niccolai, Neri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144664/
https://www.ncbi.nlm.nih.gov/pubmed/32451080
http://dx.doi.org/10.1016/j.bbrc.2020.04.007