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Treatment with 7% and 10% CO(2) enhanced expression of IL-1β, TNF-α, and IL-6 in hypoxic cultures of human whole blood

OBJECTIVE: This study investigated whether hypercapnia influenced the inflammatory response of hypoxic blood. METHODS: Human whole blood was cultured with 0.2% oxygen (O(2)) and treated with 5%, 7%, or 10% carbon dioxide (CO(2)). Interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 were eval...

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Detalles Bibliográficos
Autores principales: Ding, Hongguang, Li, Ya, Li, Xusheng, Liu, Xinqiang, Chen, Shenglong, Liu, Mengting, Zeng, Hongke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144675/
https://www.ncbi.nlm.nih.gov/pubmed/32264730
http://dx.doi.org/10.1177/0300060520912105