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Myocardial Energetics in Obesity: Enhanced ATP Delivery Through Creatine Kinase With Blunted Stress Response

BACKGROUND: Obesity is strongly associated with exercise intolerance and the development of heart failure. Whereas myocardial energetics and diastolic function are impaired in obesity, systolic function is usually preserved. This suggests that the rate of ATP delivery is maintained, but this has nev...

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Detalles Bibliográficos
Autores principales: Rayner, Jennifer J., Peterzan, Mark A., Watson, William D., Clarke, William T., Neubauer, Stefan, Rodgers, Christopher T., Rider, Oliver J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144750/
https://www.ncbi.nlm.nih.gov/pubmed/32138541
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.042770