Cargando…

Broadly applicable oligonucleotide mass spectrometry for the analysis of RNA writers and erasers in vitro

RNAs are post-transcriptionally modified by dedicated writer or eraser enzymes that add or remove specific modifications, respectively. Mass spectrometry (MS) of RNA is a useful tool to study the modification state of an oligonucleotide (ON) in a sensitive manner. Here, we developed an ion-pairing r...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagelskamp, Felix, Borland, Kayla, Ramos, Jillian, Hendrick, Alan G, Fu, Dragony, Kellner, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144906/
https://www.ncbi.nlm.nih.gov/pubmed/32083657
http://dx.doi.org/10.1093/nar/gkaa091