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Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia

Measuring minimal residual disease in cancer has applications for prognosis, monitoring treatment and detection of recurrence. Simple sequence-based methods to detect nucleotide substitution variants have error rates (about 10(−3)) that limit sensitive detection. We developed and characterized the p...

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Detalles Bibliográficos
Autores principales: Moffitt, Andrea B, Spector, Mona S, Andrews, Peter, Kendall, Jude, Alexander, Joan, Stepansky, Asya, Ma, BeiCong, Kolitz, Jonathan, Chiorazzi, Nicholas, Allen, Steven L, Krasnitz, Alex, Wigler, Michael, Levy, Dan, Wang, Zihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144909/
https://www.ncbi.nlm.nih.gov/pubmed/32083660
http://dx.doi.org/10.1093/nar/gkaa090