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Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia
Measuring minimal residual disease in cancer has applications for prognosis, monitoring treatment and detection of recurrence. Simple sequence-based methods to detect nucleotide substitution variants have error rates (about 10(−3)) that limit sensitive detection. We developed and characterized the p...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144909/ https://www.ncbi.nlm.nih.gov/pubmed/32083660 http://dx.doi.org/10.1093/nar/gkaa090 |