Crystal structure of an Escherichia coli Hfq Core (residues 2–69)–DNA complex reveals multifunctional nucleic acid binding sites

Hfq regulates bacterial gene expression post-transcriptionally by binding small RNAs and their target mRNAs, facilitating sRNA-mRNA annealing, typically resulting in translation inhibition and RNA turnover. Hfq is also found in the nucleoid and binds double-stranded (ds) DNA with a slight preference...

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Detalles Bibliográficos
Autores principales: Orans, Jillian, Kovach, Alexander R, Hoff, Kirsten E, Horstmann, Nicola M, Brennan, Richard G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144919/
https://www.ncbi.nlm.nih.gov/pubmed/32133526
http://dx.doi.org/10.1093/nar/gkaa149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144919/
https://www.ncbi.nlm.nih.gov/pubmed/32133526
http://dx.doi.org/10.1093/nar/gkaa149

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