Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-a]pyrimidines

Pyrazolo[1,5-a]pyrimidines 5a–c, 9a–c and 13a–i were synthesized for evaluation of their in vitro antimicrobial properties against some microorganisms and their immunomodulatory activity. The biological activities of pyrazolo[1,5-a]pyrimidines showed that the pyrazolo[1,5-a]pyrimidines (5c, 9a, 9c,...

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Detalles Bibliográficos
Autores principales: Naglah, Ahmed M., Askar, Ahmed A., Hassan, Ashraf S., Khatab, Tamer K., Al-Omar, Mohamed A., Bhat, Mashooq A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144935/
https://www.ncbi.nlm.nih.gov/pubmed/32245177
http://dx.doi.org/10.3390/molecules25061431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144935/
https://www.ncbi.nlm.nih.gov/pubmed/32245177
http://dx.doi.org/10.3390/molecules25061431

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