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XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways
Loss of the XPF-ERCC1 endonuclease causes a dramatic phenotype that results in progeroid features associated with liver, kidney and bone marrow dysfunction. As this nuclease is involved in multiple DNA repair transactions, it is plausible that this severe phenotype results from the simultaneous inac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144963/ https://www.ncbi.nlm.nih.gov/pubmed/32271760 http://dx.doi.org/10.1371/journal.pgen.1008555 |