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Substrate structure and computation guided engineering of a lipase for omega-3 fatty acid selectivity

Enrichment of omega-3 fatty acids (ɷ-3 FAs) in natural oils is important to realize their health benefits. Lipases are promising catalysts to perform this enrichment, however, fatty acid specificity of lipases is poor. We attempted to improve the fatty acid selectivity of a lipase from Geobacillus t...

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Detalles Bibliográficos
Autores principales: Moharana, Tushar Ranjan, Rao, Nalam Madhusudhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145112/
https://www.ncbi.nlm.nih.gov/pubmed/32271820
http://dx.doi.org/10.1371/journal.pone.0231177