Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody

OBJECTIVE: Monoclonal antibody derivatives are promising drugs for the treatment of various diseases due to their high matrix metalloproteinases (MMP) active site specificity. We studied the effects of a novel antibody, SDS3, which specifically recognizes the mature active site of MMP9/2 during vent...

Descripción completa

Detalles Bibliográficos
Autores principales: Cohen, Lena, Sagi, Irit, Bigelman, Einat, Solomonov, Inna, Aloshin, Anna, Ben-Shoshan, Jeremy, Rozenbaum, Zach, Keren, Gad, Entin-Meer, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145114/
https://www.ncbi.nlm.nih.gov/pubmed/32271823
http://dx.doi.org/10.1371/journal.pone.0231202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145114/
https://www.ncbi.nlm.nih.gov/pubmed/32271823
http://dx.doi.org/10.1371/journal.pone.0231202

Ejemplares similares