Cargando…

Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody

OBJECTIVE: Monoclonal antibody derivatives are promising drugs for the treatment of various diseases due to their high matrix metalloproteinases (MMP) active site specificity. We studied the effects of a novel antibody, SDS3, which specifically recognizes the mature active site of MMP9/2 during vent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cohen, Lena, Sagi, Irit, Bigelman, Einat, Solomonov, Inna, Aloshin, Anna, Ben-Shoshan, Jeremy, Rozenbaum, Zach, Keren, Gad, Entin-Meer, Michal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145114/ https://www.ncbi.nlm.nih.gov/pubmed/32271823 http://dx.doi.org/10.1371/journal.pone.0231202

Ejemplares similares

Correction: Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody
por: Cohen, Lena, et al.
Publicado: (2020)

Pathological presentation of cardiac mitochondria in a rat model for chronic kidney disease
por: Bigelman, Einat, et al.
Publicado: (2018)

TRPV2 knockout mice demonstrate an improved cardiac performance following myocardial infarction due to attenuated activity of peri-infarct macrophages
por: Entin-Meer, Michal, et al.
Publicado: (2017)

Introduction of correlative light and airSEM(TM) microscopy imaging for tissue research under ambient conditions
por: Solomonov, Inna, et al.
Publicado: (2014)

Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage
por: Bigelman, Einat, et al.
Publicado: (2023)

Experimental Myocardial Infarction Induces Altered Regulatory T Cell Hemostasis, and Adoptive Transfer Attenuates Subsequent Remodeling
por: Sharir, Rinat, et al.
Publicado: (2014)

Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill
por: Mohan, Vishnu, et al.
Publicado: (2021)

MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
por: Owyong, Mark, et al.
Publicado: (2019)

The Transient Receptor Potential Vanilloid 2 Cation Channel Is Abundant in Macrophages Accumulating at the Peri-Infarct Zone and May Enhance Their Migration Capacity towards Injured Cardiomyocytes following Myocardial Infarction
por: Entin-Meer, Michal, et al.
Publicado: (2014)

Gene profiling of human VEGF signaling pathways in human endothelial and retinal pigment epithelial cells after anti VEGF treatment
por: Golan, Shani, et al.
Publicado: (2014)

Differential Transcriptome Profile and Exercise Capacity in Cardiac Remodeling by Pressure Overload versus Volume Overload
por: Kim, Kyung-Hee, et al.
Publicado: (2019)

LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis
por: Klepfish, Mordehay, et al.
Publicado: (2020)

Pressure-overload-induced angiotensin-mediated early remodeling in mouse heart
por: Kim, Jeremy H., et al.
Publicado: (2017)

Sex differences in the evolution of left ventricle remodeling in rats with severe volume overload
por: Walsh-Wilkinson, Elisabeth, et al.
Publicado: (2020)

Endurance training or beta-blockade can partially block the energy metabolism remodeling taking place in experimental chronic left ventricle volume overload
por: Lachance, Dominic, et al.
Publicado: (2014)

Modification of a Volume-Overload Heart Failure Model to Track Myocardial Remodeling and Device-Related Reverse Remodeling
por: Tuzun, Egemen, et al.
Publicado: (2011)

Effects of Trandolapril on Structural, Contractile and Electrophysiological Remodeling in Experimental Volume Overload Heart Failure
por: Jarkovská, Dagmar, et al.
Publicado: (2021)

Right versus left ventricular remodeling in heart failure due to chronic volume overload
por: Havlenova, Tereza, et al.
Publicado: (2021)

Modeling the Effects of Calcium Overload on Mitochondrial Ultrastructural Remodeling
por: Strubbe-Rivera, Jasiel O., et al.
Publicado: (2021)

ECM remodelling in IBD: innocent bystander or partner in crime? The emerging role of extracellular molecular events in sustaining intestinal inflammation
por: Shimshoni, Elee, et al.
Publicado: (2015)

Left Ventricular Remodeling in Non-syndromic Mitral Valve Prolapse: Volume Overload or Concomitant Cardiomyopathy?
por: Pype, Lobke L., et al.
Publicado: (2022)

Functional and pathological characteristics of reversible remodeling in a canine right ventricle in response to volume overloading and volume unloading
por: Ishimaru, Kazuhiko, et al.
Publicado: (2014)

Biventricular Remodeling in Murine Models of Right Ventricular Pressure Overload
por: Kapur, Navin K., et al.
Publicado: (2013)

Cardiomyocyte ZKSCAN3 regulates remodeling following pressure‐overload
por: Ouyang, Xiaosen, et al.
Publicado: (2023)

Assessing the role of extracellular signal‐regulated kinases 1 and 2 in volume overload‐induced cardiac remodelling
por: Jochmann, Svenja, et al.
Publicado: (2019)

Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling
por: Kojonazarov, Baktybek, et al.
Publicado: (2013)

Unraveling the Mechanism of Cardiac Remodeling in Overloaded Heart: From Experiment to Theory
por: Cho, In-Jeong
Publicado: (2019)

Innate Immune Cells in Pressure Overload-Induced Cardiac Hypertrophy and Remodeling
por: Liu, Xin, et al.
Publicado: (2021)

Mitophagy: A Potential Target for Pressure Overload-Induced Cardiac Remodelling
por: Shao, Ruochen, et al.
Publicado: (2022)

Bilateral sympathetic stellate ganglionectomy attenuates myocardial remodelling and fibrosis in a rat model of chronic volume overload
por: Zhang, Mingjing, et al.
Publicado: (2018)

Pressure Overload-induced Cardiac Remodeling and Dysfunction in the Absence of Interleukin 6 in Mice
por: Lai, N. Chin, et al.
Publicado: (2012)

Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure
por: Patel, Bindiya, et al.
Publicado: (2017)

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice
por: Wang, Qiancheng, et al.
Publicado: (2017)

Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload
por: Jung, Hanna, et al.
Publicado: (2020)

Liver governs adipose remodelling via extracellular vesicles in response to lipid overload
por: Zhao, Yue, et al.
Publicado: (2020)

Calcium homeostasis behavior and cardiac function on left ventricular remodeling by pressure overload
por: Mazeto, I.F.S., et al.
Publicado: (2021)

Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy
por: Ma, Sai, et al.
Publicado: (2021)

Maternal Fructose Intake Exacerbates Cardiac Remodeling in Offspring with Ventricular Pressure Overload
por: Leu, Steve, et al.
Publicado: (2021)

Improvement of cardiac function and reversal of gap junction remodeling by Neuregulin-1β in volume-overloaded rats with heart failure
por: Wang, Xue-Hui, et al.
Publicado: (2012)

Evaluation of hemodynamically significant pericardial effusion by analysis of cardiac chambers volume by computed tomography
por: Granot, Yoav, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5og1vk28t9da96q78td4rjp2uq