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DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs

Genome-wide association studies have identified more than 100 SNPs that increase the risk of prostate cancer (PrCa). We identify and compare expression quantitative trait loci (eQTLs) and CpG methylation quantitative trait loci (meQTLs) among 147 established PrCa risk SNPs in primary prostate tumors...

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Detalles Bibliográficos
Autores principales: Dai, James Y., Wang, Xiaoyu, Wang, Bo, Sun, Wei, Jordahl, Kristina M., Kolb, Suzanne, Nyame, Yaw A., Wright, Jonathan L., Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145271/
https://www.ncbi.nlm.nih.gov/pubmed/32226005
http://dx.doi.org/10.1371/journal.pgen.1008667