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Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

Lipid levels are important markers for the development of cardio-metabolic diseases. Although hundreds of associated loci have been identified through genetic association studies, the contribution of genetic factors to variation in lipids is not fully understood, particularly in U.S. minority groups...

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Detalles Bibliográficos
Autores principales: Hu, Yao, Graff, Mariaelisa, Haessler, Jeffrey, Buyske, Steven, Bien, Stephanie A., Tao, Ran, Highland, Heather M., Nishimura, Katherine K., Zubair, Niha, Lu, Yingchang, Verbanck, Marie, Hilliard, Austin T., Klarin, Derek, Damrauer, Scott M., Ho, Yuk-Lam, Wilson, Peter W. F., Chang, Kyong-Mi, Tsao, Philip S., Cho, Kelly, O’Donnell, Christopher J., Assimes, Themistocles L., Petty, Lauren E., Below, Jennifer E., Dikilitas, Ozan, Schaid, Daniel J., Kosel, Matthew L., Kullo, Iftikhar J., Rasmussen-Torvik, Laura J., Jarvik, Gail P., Feng, Qiping, Wei, Wei-Qi, Larson, Eric B., Mentch, Frank D., Almoguera, Berta, Sleiman, Patrick M., Raffield, Laura M., Correa, Adolfo, Martin, Lisa W., Daviglus, Martha, Matise, Tara C., Ambite, Jose Luis, Carlson, Christopher S., Do, Ron, Loos, Ruth J. F., Wilkens, Lynne R., Le Marchand, Loic, Haiman, Chris, Stram, Daniel O., Hindorff, Lucia A., North, Kari E., Kooperberg, Charles, Cheng, Iona, Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145272/
https://www.ncbi.nlm.nih.gov/pubmed/32226016
http://dx.doi.org/10.1371/journal.pgen.1008684